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ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production.

S R DamleR K MartinC L CockburnJ C LownikJ A CarlyonA D SmithDaniel H Conrad
Published in: Allergy (2017)
Targeting ADAM10 and Notch1 on DCs represent a novel strategy for modulating TH 2 immune responses and IgE production.
Keyphrases
  • dendritic cells
  • immune response
  • cell proliferation
  • regulatory t cells
  • signaling pathway
  • cancer therapy
  • toll like receptor