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Multimorbidity, cognitive phenotypes, and Alzheimer's disease plasma biomarkers in older adults: A population-based study.

Yifei RenYuanjing LiNa TianRui LiuYi DongTingting HouCuicui LiuXiaolei HanXiaodong HanLidan WangDavide Liborio VetranoTiia NganduAlessandra MarengoniMiia KivipeltoYongxiang WangLin CongYiFeng DuChengxuan Qiu
Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
We used hierarchical clustering to generate five clusters of multimorbidity. The presence and load of multimorbidity were associated with dementia and mild cognitive impairment. Multimorbidity clusters were differentially associated with subtypes of dementia and Alzheimer's disease plasma biomarkers.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • physical activity
  • rna seq