Obinutuzumab in Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome in Children.
Claire DossierStéphanie BonnericVeronique BaudouinTheresa KwonBenjamin PrimAlexandra CambierAnne CoudercChristelle MoreauGeorges DeschenesJulien HoganPublished in: Clinical journal of the American Society of Nephrology : CJASN (2023)
These results identified low-dose obinituzumab as a promising treatment option in children with steroid-dependent or frequently relapsing nephrotic syndrome, including those resistant to rituximab. The tolerance profile of obinutuzumab appears similar to that of rituximab, but hemogram and immunoglobulin levels should be monitored.