A platform for detecting cross-resistance in antibacterial drug discovery.

Luiza H GalarionMerianne MohamadZeyad AlzeyadiChristopher P RandallAlex J O'Neill

Published in: The Journal of antimicrobial chemotherapy (2021)

By detecting cross-resistance between established and novel antibacterial agents, the CRP offers the ability to deselect compounds whose activity is substantially impaired by existing resistance mechanisms. The CRP therefore represents a useful addition to the antibacterial drug discovery toolbox.

Keyphrases

drug discovery
silver nanoparticles
anti inflammatory
high throughput