Androgen receptor splice variant 7 detected by immunohistochemical is an independent poor prognostic marker in men receiving adjuvant androgen-deprivation therapy after radical prostatectomy.

Wei OuyangYucong ZhangGongwei LongGuoliang SunMan LiuFan LiChunguang YangXing ZengJun YangXiao YuZhihua WangZheng LiuWei GuanZhiquan HuShaogang WangXiaming LiuHeng LiHua XuZhangqun Ye

Published in: Biomarker research (2021)

The presence of AR-V7 in prostate cancer tissue is independently associated with an unfavorable prognosis for PFS, OS and CSS in patients who received AHT.

Keyphrases

radical prostatectomy
prostate cancer
early stage
middle aged
stem cells
mesenchymal stem cells
smoking cessation
replacement therapy