Role of Hemidesmosomes in Oral Carcinogenesis: A Systematic Review.
Jordan NguyenTze Wei ChongHafsa ElmiJiani MaJohn MadiAsha MamgainEileen MelendezJulian MessinaNikhil MongiaSanjana NambiarTsu Jie NgHuy NguyenMichael J McCulloughFederica CanforaLorraine A O'ReillyNicola CirilloRita PaoliniAntonio CelentanoPublished in: Cancers (2023)
Heterogeneity in cell type, experimental models, and methods were observed. Alterations in hemidesmosomal components were shown to contribute to oral pre-cancer and cancer. We conclude that there is sufficient evidence for hemidesmosomes and their components to be potential biomarkers for evaluating oral carcinogenesis.