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Role of Hemidesmosomes in Oral Carcinogenesis: A Systematic Review.

Jordan NguyenTze Wei ChongHafsa ElmiJiani MaJohn MadiAsha MamgainEileen MelendezJulian MessinaNikhil MongiaSanjana NambiarTsu Jie NgHuy NguyenMichael J McCulloughFederica CanforaLorraine A O'ReillyNicola CirilloRita PaoliniAntonio Celentano
Published in: Cancers (2023)
Heterogeneity in cell type, experimental models, and methods were observed. Alterations in hemidesmosomal components were shown to contribute to oral pre-cancer and cancer. We conclude that there is sufficient evidence for hemidesmosomes and their components to be potential biomarkers for evaluating oral carcinogenesis.
Keyphrases
  • papillary thyroid
  • squamous cell
  • lymph node metastasis
  • single cell
  • young adults