A Novel PET Probe for Brown Adipose Tissue Imaging in Rodents.

Hui WangMengzhe WangKantapat ChansaenpakYang LiuHong YuanJin XieHang YinRosa T BrancaZibo LiZhanhong Wu

Published in: Molecular imaging and biology (2021)

Unlike [18F]FDG, [18F]BODIPY 1 showed prominent accumulation in BAT under both inactive and stimulated status. [18F]BODIPY 1 may serve as a valuable BAT PET agent to possibly assess BAT mitochondria density, thus BAT thermogenic capacity after further evaluation.

Keyphrases

pet ct
positron emission tomography
living cells
adipose tissue
pet imaging
fluorescent probe
computed tomography
high resolution
high fat diet
type diabetes
quantum dots
single molecule
reactive oxygen species
skeletal muscle
photodynamic therapy