Systemic cytokines are elevated in a subset of patients with irritable bowel syndrome but largely unrelated to symptom characteristics.
Sean M P BennetO PalssonWilliam E WhiteheadD A BarrowH TörnblomL ÖhmanM SimrénM A L van TilburgPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
Serum cytokines are elevated in IBS patients compared to HS. Immune activation characterizes a subset of patients, but modest associations between cytokine profile and symptoms suggest immune activity does not directly influence symptoms in IBS.