Leukocytoclastic vasculitis caused by sulfamethoxazole-trimethoprim.

Parjanya BhattNadine MontreuilAyoola OlayiwolaTanya QuirozFelipe RuizFolusakin O Ayoade

Published in: Clinical case reports (2024)

Leukocytoclastic vasculitis is a rare, small-vessel vasculitis that can be caused by sulfamethoxazole-trimethoprim. Most presentations involve skin rash but serious systemic involvement is possible. The precise mechanism is unclear but genetic and immune-based tissue damage has been postulated. The rash often resolves with discontinuation of sulfamethoxazole-trimethoprim with or without steroids.

Keyphrases

antibiotic resistance genes
oxidative stress
soft tissue
microbial community
wastewater treatment
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