Targeted DNA Methylation Analysis Facilitates Leukocyte Counts in Dried Blood Samples.

Wouter H G HubensTiago MaiéMatthis SchnitkerLedio BocovaDeepika PuriMartina WessiepeJan KramerLothar Rink Steffen Koschmieder Ivan G Costa Wolfgang Wagner

Published in: Clinical chemistry (2023)

The advanced selection of cell-type specific CpGs and utilization of digital droplet PCR analysis provided accurate epigenetic blood counts. Analysis of dried blood facilitates self-sampling with a finger prick, thereby enabling easier accessibility to testing.

Keyphrases

dna methylation
gene expression
peripheral blood
high resolution
single cell
mass spectrometry
drug delivery