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High-dose vitamin D supplementation in multiple sclerosis - results from the randomized EVIDIMS (efficacy of vitamin D supplementation in multiple sclerosis) trial.

Jan DörrPriscilla Bäcker-KoduahKlaus-Dieter WerneckeElke BeckerFrank HoffmannJürgen FaissBernd BrockmeierOlaf HoffmannKerstin AnvariJens WuerfelSophie Käthe PiperJudith Bellmann-StroblAlexander Ulrich BrandtFriedemann Paul
Published in: Multiple sclerosis journal - experimental, translational and clinical (2020)
The results neither support nor disprove a therapeutic benefit of high-dose VD supplementation but provide a basis for sound sample size estimations in future confirmatory studies. www.clinicaltrials.gov/NCT01440062.
Keyphrases
  • high dose
  • multiple sclerosis
  • phase iii
  • stem cell transplantation
  • low dose
  • phase ii
  • open label
  • double blind
  • white matter
  • clinical trial
  • study protocol
  • placebo controlled
  • current status
  • case control