Blast size-specific flowcytometric ploidy assessment using FxCycleTM Violet dye and its correlation with conventional cytogenetic ploidy in pediatric precursor B-lineage acute lymphoblastic leukemia patients.

Karthik BommannanJhansi Rani ArumugamTeena KoshyVenkatraman RadhakrishnanTenali Gnana SagarShirley Sundersingh

Published in: International journal of laboratory hematology (2020)

FCM-ploidy assessment using FxCV dye is a reliable assay and the results closely concur with CG-based ploidy stratification and risk assessment. Using blast size-assisted DNA content analysis, the results of FCM-ploidy analysis can be further fine-tuned.

Keyphrases

acute lymphoblastic leukemia
risk assessment
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
high throughput
single molecule
single cell
circulating tumor
patient reported outcomes
young adults
aqueous solution
circulating tumor cells