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Rupatadine ameliorated ulcerative colitis in rats via modulation of platelet-activatiweng factor/interleukin-6/vascular endothelial growth factor signalling pathway.

Mohamed A IbrahimAlyaa Abdelfattah AbdelmonaemSeham A Abdel-GaberHeba M HafezSara Mohamed Naguib Abdel HafezWalaa Yehia Abdelzaher
Published in: The Journal of pharmacy and pharmacology (2022)
RUP protects against UC by reducing oxidative stress and by regulating the PAF/IL-6/VEGF pathway.
Keyphrases
  • vascular endothelial growth factor
  • ulcerative colitis
  • oxidative stress
  • endothelial cells
  • dna damage
  • diabetic rats
  • ischemia reperfusion injury
  • induced apoptosis
  • signaling pathway