Whether to maintain or strengthen the treatment for pyoderma gangrenosum ulcerative type may depend on the response after two to four-week treatment intervention: The outcome of three cases with details clinical course.

Determining whether the treatment intensity needs to be increased or can be maintained at a constant level may be suggested after 2-4 weeks of treatment. The use of TNF-α inhibitor, removal of necrotic tissue, and skin grafting may promote epithelialization.