Alternating pattern of rhino-orbital-cerebral mucormycosis with COVID-19 in diabetic patients.
Çağlar EkerÖzgür TarkanOzgur SurmeliogluMuhammed DagkiranIlda TanriseverSevinc Puren Yucel KarakayaBurak UlasElvan OnanAysun Hatice UguzSüleyman ÖzdemirPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2022)
With COVID-19, progressive mucormycosis accompanied by orbital and intracranial involvement is observed more frequently. However, on the contrary, the mortality rate in COVID-19-associated mucormycosis is considerably lower than expected. The fact that temporary immune suppression can be ameliorated with adequate supportive treatment and liposomal amphotericin-B which can be given to patients in high doses may explain this situation. It has been attained hints that the essential factor in the treatment of COVID-19-associated ROCM is the control of the underlying disease and to be cautious in the decision of early aggressive surgery.