Genetically Predicted Body Mass Index and Mortality in COPD.

Jingzhou ZhangMatthew MollBrian D HobbsPer BakkeElizabeth A ReganHanfei XuJosée DupuisJoe W ChilesMerry-Lynn N McDonaldMiguel J DivoEdwin K SilvermanBartolome R CelliGeorge T O'ConnorMichael H Cho

Published in: American journal of respiratory and critical care medicine (2024)

In people with COPD, higher genetically predicted BMI is associated with higher cardiovascular mortality but not respiratory mortality. Individuals with discordantly low BMI have higher all-cause and respiratory mortality compared to those with concordant BMI.

Keyphrases

cardiovascular events
body mass index
chronic obstructive pulmonary disease
risk factors
weight gain
lung function
cardiovascular disease
type diabetes
coronary artery disease
physical activity
weight loss