Attenuated Sympathetic Blood Pressure Transduction in Patients With Treated Heart Failure With Reduced Ejection Fraction.
Massimo NardoneCatherine F NotariusMark B BadrovPhilip J MillarJohn S FlorasPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
Treated HFrEF is associated with lower sympathetic-BP transduction, even when MSNA is not elevated, and diminishes further with disease progression. These adaptations may serve to limit the adverse consequences of oscillatory surges in sympathetic vasoconstrictor discharge on stroke volume.