A pan-genotype hepatitis C virus viral vector vaccine generates T cells and neutralizing antibodies in mice.
Timothy DonnisonJoey McGregorSenthil K ChinnakannanClaire L HutchingsRob J CenterPantelis PoumbouriosPaul KlenermanHeidi E DrummerEleanor BarnesPublished in: Hepatology (Baltimore, Md.) (2022)
These data are an important step forward for the development of a pan-genotype HCV vaccine to elicit T cells and nAbs for future assessment in humans.