Automatic Estimation of the Most Likely Drug Combination in Electronic Health Records Using the Smooth Algorithm: Development and Validation Study.
Dan OuchiMaria Giner-SorianoAinhoa Gómez-LumbrerasCristina Vedia-UrgellFerràn TorresRosa Morros-PedrosPublished in: JMIR medical informatics (2022)
The smooth algorithm is an automated approach that standardizes, simplifies, and improves data processing in drug exposition studies using EHRs. This algorithm can be generalized to almost any pharmacological medication and model the drug exposure to facilitate the detection of treatment switches, discontinuations, and terminations throughout the study period.