Chiral Silanols: Strategies and Tactics for Their Synthesis.
Jihui GaoChuan HePublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Silanols are valuable and important compounds, which have found widespread applications in the field of materials science, synthetic chemistry, and medicinal chemistry. Although a handful of approaches have been developed for the synthesis of various silanols, access to enantioenriched silicon-stereogenic silanols remains underdeveloped. This Concept article intends to summarize and highlight recent advances in the construction of silicon-stereogenic silanols and endeavors to encourage further research in this area.
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