Machine learning reveals the rules governing the efficacy of mesenchymal stromal cells in septic preclinical models.
Diksha GakharHimanshu JoshiDiksha MakkarNeelam TanejaAmit AroraAruna RakhaPublished in: Stem cell research & therapy (2024)
The rules from the generated graph models indicated that survival rates, post-MSC-infusion, are influenced by factors like source, dosage, time of infusion, pre-Interleukin-6 (IL-6)/ Tumour Necrosis Factor- alpha (TNF-α levels, etc. CONCLUSION: This approach provides important information for optimization of MSCs based treatment strategies that may help the researchers design their experiments.