Development and Use of an Ex-Vivo In-Vivo Correlation to Predict Antiepileptic Drug Clearance in Patients Undergoing Continuous Renal Replacement Therapy.
Shamir N KalariaMichael ArmahizerPaul McCarthyNeeraj BadjatiaJogarao V GobburuMathangi GopalakrishnanPublished in: Pharmaceutical research (2022)
The findings indicate that an ex-vivo study can be used as a surrogate to predict in-vivo levetiracetam and lacosamide clearance in patients receiving CRRT.
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