Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B-cell acute lymphoblastic leukemia.

Riccardo MoiaMariangela GrecoPaola BoggioneMaura NicolosiRiccardo BrunaAndrea PatriarcaGianluca GaidanoMonia Lunghi

Published in: Clinical case reports (2020)

Patients with B-lineage acute lymphoblastic leukemia treated with pegasparaginase-containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

Keyphrases

acute lymphoblastic leukemia
drug induced
cerebrospinal fluid
allogeneic hematopoietic stem cell transplantation
single cell
cell fate