Treatment with Methylphenidate for Attention Deficit Hyperactivity Disorder (ADHD) and the Risk of All-Cause Poisoning in Children and Adolescents: A Self-Controlled Case Series Study.
Le GaoKenneth Keng Cheung ManEsther Wai Yin ChanCeline Sze Ling ChuiXue LiDavid R CoghillKam Lun Ellis HonMan-Li TseTerry Yat-Sang LumKirstie H T W WongPatrick IpIan Chi Kei Ck WongPublished in: CNS drugs (2021)
The risk of all-cause poisoning was higher shortly before and after the first MPH prescription and became lower during the subsequent prescription period. Our results do not support an association between the use of MPH and an increased risk of all-cause poisoning in children and adolescents and, in fact, suggest that longer-term use of MPH may be associated with a lower risk of all-cause poisoning, although this latter finding requires further study.