Spinal motoneurons respond aberrantly to serotonin in a rabbit model of cerebral palsy.
E J ReedichL T GenryP R SteeleE Mena AvilaL DowalibyA DrobyshevskyM ManuelKatharina A QuinlanPublished in: bioRxiv : the preprint server for biology (2023)
receptors than control MNs, which could account for the more robust excitatory response of HI MNs. These results suggest that after HI injury, the increased serotonin could trigger a cascade of events leading to muscle stiffness and altered motor unit development.