Brain structural covariance network features are robust markers of early heavy alcohol use.
Jonatan Ottino-GonzalezRenata Basso CupertinoZhipeng CaoSage HahnDevarshi PancholiMatthew D AlbaughTy BrumbackFiona C BakerSandra A BrownDuncan B ClarkMassimiliano de ZambottiDavid B GoldstonBeatriz LunaBonnie J NagelKate B NoonerKilian M PohlSusan F TapertWesley Kurt ThompsonTerry L JerniganPatricia J ConrodScott MackeyHugh GaravanPublished in: Addiction (Abingdon, England) (2023)
Structural covariance network (SCN) differences in the brain appear to constitute an early marker of heavy alcohol use in three new data sets and, more generally, demonstrate the utility of SCN-derived metrics to detect brain-related psychopathology.