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HBV REPLICATION DURING TENOFOVIR THERAPY IS FREQUENT IN HIV/HBV-COINFECTION.

Eveline HofmannBernard SurialNoémie Boillat-BlancoHuldrych F GünthardMarcel StöckleEnos BernasconiPatrick SchmidAlexandra CalmyFranziska Suter-RinikerAndri RauchGilles WandelerCharles Béguelinnull null
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
In the Swiss HIV Cohort Study, 61/222 (27%) HIV-suppressed persons with chronic hepatitis B virus (HBV) infection had HBV replication after two years on tenofovir, of whom 77% were suppressed thereafter. Self-reported adherence to therapy and HBV viral load at tenofovir initiation were predictors of persistent replication.
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