Efficacy of Palmitoylethanolamide, Epilobium and Calendula suppositories for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome type III.

Giuseppe MorgiaArturo Lo GiudiceMaurizio CarrinoSalvatore VoceAndrea CocciGiulio RealeAndrea MinerviniSebastiano CiminoGiorgio Ivan RussoFrancesca Zingone

Published in: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica (2024)

In this observational study, we showed the clinical efficacy of the treatment with PEA, Epilobium and Calendula, 1 suppository/die for 1 month, in patients with CP/CPPS III. The benefits of this treatment could be related to the reduction of inflammatory cells in the urine that could imply a reduction of inflammatory cytokines. These results should be confirmed in further studies with greater sample size.

Keyphrases

induced apoptosis
type iii
oxidative stress
cell death
signaling pathway
combination therapy
rectal cancer
drug induced