Analytical and Clinical Validation of Cell-Free Circulating Tumor DNA Assay for the Estimation of Tumor Mutational Burden.
Kwang Seob LeeJieun SeoChoong-Kun LeeSaeam ShinZisun ChoiSeungki MinJun Hyuek YangWoo Sun KwonWoobin YunMi Ri ParkJong Rak ChoiHyun Cheol ChungSeung Tae LeeSun Young RhaPublished in: Clinical chemistry (2022)
The TMB500 assay is an accurate and reliable ctDNA assay for many clinical purposes. It may be useful for guiding the treatment of cancers with diverse genomic profiles, estimating TMB in immune therapy, and disease monitoring.