Development and application of an elastic net logistic regression model to investigate the impact of cardiac substructure dose on radiation-induced pericardial effusion in patients with NSCLC.
Joshua S NiedzielskiXiong WeiTing XuDaniel R GomezZhongxing LiaoJames A BanksonStephen Y LaiLaurence E CourtJinzhong YangPublished in: Acta oncologica (Stockholm, Sweden) (2020)
We developed and evaluated elastic net regression toxicity models of radiation-induced PCE. We found the model type that included cardiac substructure dose had superior predictive performance. A final toxicity model that included cardiac substructure dose metrics was developed and reported for comparison with external datasets.