Identification of Key Genes for Pyroptosis-Induced Salivary Gland Inflammation in Sjogren's Syndrome Based on Microarray Data and Immunohistochemistry Analysis.

Kaiyuan ZhangZi-Yue Luo Xinchao Zhu Xin-Yi Yao Ding-Qi LuLiying ChenTao HongYating RenXin-Chang Wang

Published in: Journal of inflammation research (2023)

Our study revealed enhanced levels of pyroptosis in the SS. GZMA and GBP1 were identified as candidate genes for pyroptosis-induced inflammation of the SG in SS, which may be used as biomarkers or potential therapeutic targets for SS.

Keyphrases

oxidative stress
diabetic rats
high glucose
bioinformatics analysis
genome wide
electronic health record
endothelial cells
big data
machine learning
case report
risk assessment
dna methylation
human health
data analysis