Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells.

Angela VermaYau-Min LamYun-Chung LeungXiaohui HuXin ChenEdwin CheungKin Yip Tam

Published in: The Journal of pharmacy and pharmacology (2018)

Our results suggested that dichloroacetate and arginase combination exhibited enhanced anti-cancer effects in preclinical breast cancer models which may offer an additional treatment option for breast cancer.

Keyphrases

breast cancer cells
nitric oxide synthase
stem cells
nitric oxide
replacement therapy