Activation of GSK3 Prevents Termination of TNF-Induced Signaling.
Bastian WelzRolf BikkerLeonie HoffmeisterMareike DiekmannMartin ChristmannKorbinian BrandRené HuberPublished in: Journal of inflammation research (2021)
Our results suggest that GSK3 activation is involved in preventing the termination of TNF-induced signaling. Our data demonstrate that activation of GSK3 - either pathophysiologically or pharmacologically induced - may destroy the finely balanced condition necessary for the termination of inflammation-associated signaling.