A Longitudinal Multiinstitutional Study of Vulvar Lichen Sclerosus: From Childhood to Perimenopause.
Jacopo Di GiuseppeGiovanni Delli CarpiniLuca GiannellaTomas TerenziMariasole FicheraFederica RagnoAnna CampanatiVeronica BoeroCarlotta CaiaElisa PescePaolo VercelliniBarbara GardellaMattia DominoniArsenio SpinilloFrancesco SopracordevoleNicolò ClementeAnna Del FabroRiccardo RossiMonica CorazzaAlessandro BorghiRuby MartinelloPantaleo GrecoGiuseppe RizzoAnna Angela CriscuoloIlenia MappaEnrico MatteiniElisabetta BottiElena CampioneLuca BianchiAndrea CiavattiniPublished in: Journal of lower genital tract disease (2024)
Vulvar lichen sclerosus is a chronic condition that can cause vulvar changes that result in severe morbidity and affects sexual function and quality of life, even before menopause. Vulvar lichen sclerosus continues to be misdiagnosed in this population. This may lead to an average delay from symptom onset to diagnosis. Evaluating clinical manifestations of VLS in premenarchal and postmenarchal age allowed us to find different clinical characteristics between the 2 periods suggestive of the diagnosis.