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Parameters predicting [18F]PSMA-1007 scan positivity and type and number of detected lesions in patients with biochemical recurrence of prostate cancer.

Niloefar Ahmadi BidakhvidiAnnouschka LaenenSander JentjensChristophe M DerooseKoen Van LaereLiesbeth De WeverCindy MaiCharlien BerghenGert De MeerleerKarin HaustermansSteven JoniauWouter EveraertsKarolien Goffin
Published in: EJNMMI research (2021)
[18F]PSMA-1007-PET/CT showed a high positivity rate in patients with biochemically recurrent PCa. PSA value and PSA velocity were significant predictors of scan positivity as well as of the presence and number of bone and soft tissue lesions and the number of LN lesions. Our findings can guide clinicians in optimal patient selection for [18F]PSMA-1007-PET/CT and support further research leading to the development of a prediction nomogram.
Keyphrases
  • pet ct
  • prostate cancer
  • soft tissue
  • radical prostatectomy
  • computed tomography
  • positron emission tomography
  • lymph node metastasis
  • magnetic resonance
  • body composition
  • blood flow
  • contrast enhanced