Systematic Review and Meta-Analysis on the Associations of Polypharmacy and Potentially Inappropriate Medication With Adverse Outcomes in Older Cancer Patients.

Li-Ju ChenKira TraresDana Clarissa LaetschThi Ngoc Mai NguyenHermann BrennerBen Schöttker

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)

Polypharmacy was found to be associated with several adverse outcomes and PIM use with all-cause mortality in older cancer patients. However, these results should be interpreted with caution because about three-quarters of the studies identified did not adjust for comorbidity and are prone to confounding by indication.

Keyphrases

community dwelling
adverse drug
middle aged
physical activity
healthcare
emergency department