Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults.

Yunhua L MullerRobert L HansonDarin MahkeePaolo PiaggiSayuko KobesWen-Chi HsuehWilliam C KnowlerClifton BogardusLeslie J Baier

Published in: Obesity (Silver Spring, Md.) (2020)

There is a negative relationship between IGF-II levels and BMI, in which the correlation is stronger at older ages. The association between genetic risk for BMI and IGF-II levels suggests that this correlation may be due to an effect of obesity on IGF-II.

Keyphrases

growth factor
body mass index
weight gain
binding protein
metabolic syndrome
type diabetes
pi k akt
insulin resistance
physical activity
weight loss
gene expression
dna methylation
cell proliferation
copy number