Kikuchi-Fujimoto disease during early pregnancy.
Go IchikawaYasuyuki NegishiFumihisa ChishimaShunji SuzukiPublished in: The journal of obstetrics and gynaecology research (2024)
Kikuchi-Fujimoto disease (KFD) is rare during pregnancy. It is characterized by necrotizing lymphadenitis and often occurs in young Asian women. We report a case of KFD during pregnancy, which was difficult to diagnose. A 37-year-old pregnant female (gestational week [GW] 7 +5 ) was admitted to our hospital because of hyperemesis gravidarum. On the eighth day of hospitalization (GW 8 +6 ), she suddenly developed a fever (38.0°C) with skin rash and posterior pharynx redness. Blood tests showed pancytopenia and abnormal liver function. The patient was misdiagnosed with severe Epstein-Barr virus infection and administered with prednisolone. Subsequently, cervical lymphadenopathy was observed, and biopsy results led to the diagnosis of KFD. Thereafter, her symptoms improved, and she was discharged at GW 13 +4 . KFD must be included as a differential diagnosis for patients with fever, abnormal liver function, and pancytopenia during pregnancy.
Keyphrases
- epstein barr virus
- pregnant women
- diffuse large b cell lymphoma
- pregnancy outcomes
- weight gain
- polycystic ovary syndrome
- fine needle aspiration
- early onset
- emergency department
- clinical trial
- ultrasound guided
- metabolic syndrome
- skeletal muscle
- sleep quality
- middle aged
- wound healing
- preterm birth
- depressive symptoms
- study protocol
- breast cancer risk