Chromatographic Techniques for Assessment of Bisoprolol Fumarate and Perindopril Arginine in Solid Formulations Under Various Stress Conditions and Application to Six Sigma, Content Uniformity, and Comparative Dissolution Approaches.

This study is innovative since it is the first to establish and validate specific and reproducible UPLC and HPLC methods for the concurrent quantitative of the studied drugs in their binary mixture and application to lean six sigma, content uniformity, and comparative dissolution approaches.