Impact of extracellular matrix stiffness on genomic heterogeneity in MYCN-amplified neuroblastoma cell line.

Amparo López-CarrascoSusana Martín-VañóRebeca Burgos-PanaderoEzequiel MonferrerAna P BerbegallBeatriz Fernández-BlancoSamuel NavarroRosa Noguera

Published in: Journal of experimental & clinical cancer research : CR (2020)

Focus on heterogeneous intratumor segmental chromosome aberrations and mutations, as a mirror image of tumor microenvironment, is a vital area of future research.

Keyphrases

extracellular matrix
copy number
current status
deep learning
single cell
genome wide
dna methylation
gene expression
machine learning