Cancer has been regarded as one of the most intractable diseases worldwide and threatens human health and life. Photothermal/Photodynamic therapy (PTT and PDT) have emerged as reliable and effective strategies in cancer treatment with the superiorities of non-invasiveness, slight side effects, and high treatment efficiency. Herein, a nanocomposite (PBCN) was fabricated via electrostatic interaction between Prussian blue nanoparticles (PBNPs) and graphitic carbon nitride (g-C 3 N 4 ), and the resulting PBCN possessed good photothermal properties and excellent photodynamic effects with 808 nm irradiation. Furthermore, it exhibits excellent fluorescence imaging ability in cells, highlighting its potential as a powerful imaging agent in the biomedical field. Combination with a photothermal material, photosensitizer, and fluorescence imaging agent would thus allow PBCN to realize fluorescence imaging-guided PTT/PDT, showing an outstanding theranostic effect on cancer cells.
Keyphrases
- photodynamic therapy
- fluorescence imaging
- combination therapy
- visible light
- human health
- cancer therapy
- reduced graphene oxide
- risk assessment
- quantum dots
- induced apoptosis
- climate change
- high resolution
- gold nanoparticles
- cell cycle arrest
- radiation therapy
- signaling pathway
- oxidative stress
- molecular dynamics simulations
- young adults
- mass spectrometry
- smoking cessation