Changing character and waning impact of COVID-19 at a tertiary centre in Cape Town, South Africa.
Lucas E HermansPetro BooysenLinda BolokoMarguerite AdriaanseTimothy J de WetAimee R LifsonNaweed WadeeNectarios S PapavarnavasGert J K MaraisNei-Yuan HsiaoMichael-Jon RossleeGregory SymonsGregory L CalligaroArash IranzadehRobert John WilkinsonNtobeko A B NtusiCarolyn WilliamsonMary-Ann DaviesGraeme MeintjesSean WassermanPublished in: Southern African journal of infectious diseases (2023)
This study summarises clinical characteristics associated with SARS-CoV-2 variants during the COVID-19 pandemic at a South African tertiary hospital, demonstrating a waning impact of COVID-19 on healthcare services over time despite epidemic waves driven by new variants. Findings suggest the absence of increasing virulence from later variants and protection from population and individual-level immunity.
Keyphrases
- sars cov
- south africa
- healthcare
- copy number
- coronavirus disease
- respiratory syndrome coronavirus
- hiv positive
- escherichia coli
- pseudomonas aeruginosa
- primary care
- staphylococcus aureus
- dna methylation
- antimicrobial resistance
- biofilm formation
- gene expression
- social media
- cystic fibrosis
- hepatitis c virus
- affordable care act