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Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response.

Robert Carreras-TorresAndre E KimYi LinVirginia Díez-ObreroStephanie A BienConghui QuJun WangNiki L DimouElom Kouassivi AglagoDemetrius AlbanesVolker ArndtJames W BaurleySonja I BerndtStéphane BézieauD Timothy BishopEmmanouil C BourasHermann BrennerArif BudiartoPeter T CampbellGraham CaseyAndrew T ChanJenny Chang-ClaudeXuechen ChenDavid V ContiChristopher H DampierMatthew A M DevallDavid A DrewJane C FigueiredoSteven J GallingerGraham G GilesStephen B GruberAndrea GsurMarc J GunterTabitha A HarrisonAkihisa HidakaMichael HoffmeisterJeroen R HuygheMark E JenkinsKristina M JordahlEric S KawaguchiTemitope O KekuAnshul KundajeLoic Le MarchandJuan Pablo LewingerLi LiBharuno MahesworoJohn L MorrisonNeil MurphyHongmei NanRami NassirPolly A NewcombMireia Obon-SantacanaShuji OginoJennifer OseRish K PaiJulie R PalmerNikos PapadimitriouBens PardameanAnita R PeoplesPaul D P PharoahElizabeth A PlatzGadi RennertEdward A Ruiz-NarvaezLori C SakodaPeter C ScacheriStephanie L SchmitRobert E SchoenAnna ShcherbinaMartha L SlatteryMariana C SternYu-Ru SuCatherine M TangenDuncan C ThomasYu TianKonstantinos K TsilidisCornelia M UlrichFranzel J B van DuijnhovenBethany Van GuelpenKala VisvanathanPavel VodickaTjeng Wawan CenggoroStephanie J WeinsteinEmily WhiteAlicja WolkMichael O WoodsLi HsuUlrike PetersVictor MorenoW James Gauderman
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)
These findings can guide potential prevention treatments.
Keyphrases
  • genome wide
  • dna methylation
  • immune response
  • copy number
  • oxidative stress
  • smoking cessation
  • toll like receptor
  • dendritic cells
  • climate change
  • human health