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Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp.

Shujie WangYuying DengXiaoyan XieJing MaYanan HouXinjie ZhaoWeiqiong GuJie HongWeiqing WangGuowang XuGuang NingYanyun GuYifei Zhang
Published in: Journal of diabetes (2018)
The abnormal BA composition in T2DM subjects and its correlation with insulin secretion during the clamp suggest an interaction between BA signals and insulin secretion capacity, and the potential to use fasting plasma BA composition indices to predict and evaluate the progression and prognosis of T2DM.
Keyphrases
  • type diabetes
  • glycemic control
  • blood glucose
  • insulin resistance
  • cardiovascular disease
  • blood pressure
  • weight loss
  • human health