Login / Signup

A Concise Synthesis of a BODIPY-Labeled Tetrasaccharide Related to the Antitumor PI-88.

Juan VenturaClara UrielAna Maria GómezEdurne Avellanal-ZaballaJorge BañuelosInmaculada García-MorenoJose Cristobal Lopez
Published in: Molecules (Basel, Switzerland) (2021)
A convergent synthetic route to a tetrasaccharide related to PI-88, which allows the incorporation of a fluorescent BODIPY-label at the reducing-end, has been developed. The strategy, which features the use of 1,2-methyl orthoesters (MeOEs) as glycosyl donors, illustrates the usefulness of suitably-designed BODIPY dyes as glycosyl labels in synthetic strategies towards fluorescently-tagged oligosaccharides.
Keyphrases
  • living cells
  • fluorescent probe
  • quantum dots
  • single molecule
  • computed tomography
  • pet imaging