The Role of the Kynurenine Pathway in the (Patho) physiology of Maternal Pregnancy and Fetal Outcomes: A Systematic Review.

Sofie Km van ZundertMichelle BroekhuizenAshley Jp SmitLenie van RossemMina MirzaianSten P WillemsenAh Jan DanserYolanda B De RijkeIrwin Km ReissDaphne MerkusRégine Pm Steegers-Theunissen

Published in: International journal of tryptophan research : IJTR (2022)

KP metabolite concentrations were altered in a variety of maternal pregnancy and fetal complications. This review implies that physiological pregnancy requires a tight balance of KP metabolites, and that disturbances in either direction are associated with adverse maternal pregnancy and fetal outcomes.

Keyphrases

pregnancy outcomes
preterm birth
pregnant women
birth weight
emergency department
risk factors
physical activity
gestational age
skeletal muscle
adipose tissue
drug induced