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Essential Characteristics of Pharmacogenomics Study Publications.

Caroline F ThornMichelle Whirl-CarrilloHouda HachadJulie A JohnsonEllen M McDonaghMark J RatainMary V RellingStuart A ScottRuss B AltmanTeri E Klein
Published in: Clinical pharmacology and therapeutics (2019)
Pharmacogenomics (PGx) can be seen as a model for biomedical studies: it includes all disease areas of interest and spans in vitro studies to clinical trials, while focusing on the relationships between genes and drugs and the resulting phenotypes. This review will examine different characteristics of PGx study publications and provide examples of excellence in framing PGx questions and reporting their resulting data in a way that maximizes the knowledge that can be built on them.
Keyphrases
  • clinical trial
  • healthcare
  • adverse drug
  • emergency department
  • machine learning
  • genome wide
  • big data
  • transcription factor
  • deep learning
  • open label
  • phase ii