Association of Hyper-Polypharmacy With Clinical Outcomes in Heart Failure With Preserved Ejection Fraction.
Masatoshi MinamisawaBrian Lee ClaggettKota SuzukiSheila M HegdeAmil M ShahAkshay S DesaiEldrin F LewisSanjiv J ShahNancy K SweitzerJames C FangInder S AnandEileen O'MearaJean-Lucien RouleauBertram PittMarc A PfefferScott D SolomonOrly VardenyPublished in: Circulation. Heart failure (2021)
Hyper-polypharmacy was common and associated with an elevated risk of hospitalization for any reason and any serious adverse events in patients with heart failure with preserved ejection fraction. There were no significant associations between polypharmacy status and mortality.