Effective delivery and selective insecticidal activity of double-stranded RNA via complexation with diblock copolymer varies with polymer block composition.

Charlotte E PugsleyR Elwyn IsaacNicholas J WarrenMartin StaceyCalum T J FergusonKaat CappelleRosa Dominguez-EspinosaOlivier J Cayre

Published in: Pest management science (2023)

Thus, we provide evidence that dsRNA complexation with diblock copolymers is a promising strategy for RNAi-based species-specific pest control, however, optimisation of polymer composition is essential for RNAi success. This article is protected by copyright. All rights reserved.

Keyphrases

nucleic acid
binding protein
drug release