Effect of janus kinase inhibitors and methotrexate combination on malignancy in patients with rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trials.

Vinod SolipuramAkhila MohanRoshniben PatelRuoning Ni

Published in: Auto- immunity highlights (2021)

The adjunction of JAKi to MTX is not associated with an increased risk of malignancy when compared to MTX alone. There is no increased risk of SAE and deaths when compared to MTX alone in patients with RA.

Keyphrases

rheumatoid arthritis
high dose
disease activity
low dose
systemic lupus erythematosus
idiopathic pulmonary fibrosis